Frequently asked questions

SKYTROFA is a prescription medicine used for:

• The replacement of growth hormone in children 1 year old or older who weigh at least 26 pounds (11.5 kilograms) with growth hormone deficiency (GHD)
• The replacement of growth hormone in adults with growth hormone deficiency (GHD)

SKYTROFA is the only long-acting growth hormone treatment for aGHD that requires no refrigeration for up to 6 months* and is preservative free.

SKYTROFA is for adults diagnosed with GHD. Your doctor will help you determine if SKYTROFA is an appropriate treatment option.

The SKYTROFA Auto-Injector delivers a single-use injection with no dose dialing—while automated cues guide you through each step.

Because the cartridges don’t need to be refrigerated, they can go wherever you go, with no need for ice packs or cold storage for up to 6 months*.

For more information, read the Quick Reference Guide.

The battery icon on your auto-injector will always let you know when it is time to charge the device. Once the auto-injector has charged for 15 minutes and the battery icon flashes green, the device is ready to use for at least 1 injection after the charging cable is unplugged.

When the battery icon shows constant green, the auto-injector is fully charged and lasts for at least 3 injections based on one injection per week.

Once your doctor prescribes SKYTROFA, they will also enroll you in the Ascendis Signature Access Program^® (A·S·A·P). Through A·S·A·P, you will receive personalized support to help coordinate device training and provide injection assistance.

For any questions, please call 1-844-442-7236.

No, SKYTROFA cartridges do not need to be refrigerated for up to 6 months.* With SKYTROFA, you can store your medicine at home or take it on the go.

If you miss your dose, SKYTROFA can be taken up to 2 days after your regular injection day. It can also be taken 2 days before your regular injection day. However, you should always go back to your regular injection day after taking a missed dose. If more than 2 days have passed from the scheduled day, skip the dose and administer the next dose on the regularly scheduled day. At least 5 days should elapse between doses.

To help avoid missing doses, sign up for weekly injection text reminders.

SKYTROFA is available in 14 dosage strengths: 0.7mg, 1.4mg, 1.8mg, 2.1mg, 2.5mg, 3mg, 3.6mg, 4.3mg, 5.2mg, 6.3mg, 7.6mg, 9.1mg, 11mg, and 13.3mg. Your doctor will help find the dose that’s right for you and make any adjustments if needed.

Talk with your doctor about once-weekly SKYTROFA.

Learn more about getting started.

Health insurance comes in many forms:

• Group-sponsored Health Insurance: Offered through employers or spouse/domestic partner’s employer.
• Private Coverage: Directly purchased from insurance carriers.
• Exchange Plans: Purchased through state or federal exchanges, with possible subsidies based on income.
• Medicare: A federal program for individuals aged 65 and older.
• Medicaid and Children’s Health Insurance Program (CHIP): Available for qualifying individuals with disabilities or conditions.

Health insurance plans can be classified into 4 primary categories, each with its own set of features:

• Health Maintenance Organization (HMO): Limited to in-network providers, requires a primary care physician (PCP), and referrals for specialists.
• Exclusive Provider Organization (EPO): Restricts care to in-network providers but doesn’t require a PCP or referrals.
• Point of Service (POS): Allows both in-network and out-of-network care, but PCP and referrals are needed.
• Preferred Provider Organization (PPO): Provides in-network and out-of-network coverage without requiring a PCP or referrals.

With a fully insured plan, your employer pays a fixed monthly premium to an insurance company, covering plan administration and claims. The insurance company bears the loss if claims exceed expectations.

With a self-funded plan, your employer pays a monthly fee to an insurance company for administration and claims adjudication but covers the actual claims costs. The employer benefits if costs stay below expectations and has more flexibility in plan features.

Health insurance companies use various strategies to manage specialty medication costs, including prior authorizations and step therapy. Stay informed about new trends, such as co-pay accumulators, and explore financial assistance programs.

Watch the New Rx Trends chapter in this video for more details.

To understand your coverage, review the Summary of Benefits and Coverage (SBC) provided by the insurance company. It outlines co-pays, deductibles, and out-of-pocket maximums.

For detailed coverage information, you can get the medical policy from the insurance company’s website or call their Member Services department.

During open enrollment, consider the following factors to make the best decisions for your healthcare needs:

• Estimate your annual expenses, including co-pays, coinsurance, deductibles, and out-of-pocket maximums.
• Compare total costs of different plans, including in-network and out-of-network expenses.
• Check if your prescriptions, especially growth hormone medications, are covered similarly in each plan.
• Attend open enrollment events, ask questions, and seek assistance to understand any changes to the plan.

Be proactive in the prior authorization and appeals process by documenting all communications between you and your insurance company.

If you face a denial, involve your doctor, focus on medical necessity, and provide evidence to support your appeal. Always advocate for yourself to get the medicine you need. For any questions, contact A·S·A·P by calling 1-844-442-7236.

Various advocacy organizations like The Magic Foundation, Human Growth Foundation, and NORD offer support and educational resources. Assistance and advocacy can help you have access to the best healthcare options.

Visit the Resources page to explore some of these organizations.