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SKYTROFA® is also available for adults with growth hormone deficiency
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Starting SKYTROFA

Whether you’re considering SKYTROFA, or already getting started with treatment, check out these helpful resources.

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With SKYTROFA, you’ll receive personalized support every step of the way

From navigating insurance to getting SKYTROFA delivered directly to your doorstep, we’re here to help guide and assist you.

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Prescription and Enrollment

Once you and your child’s doctor have decided that SKYTROFA is the right treatment option, your doctor will write a prescription and enroll you in the Ascendis Signature Access Program® (A·S·A·P). At that time, you’ll be assigned an A·S·A·P representative.

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Insurance Authorization

Your representative will verify your insurance coverage. Once completed, the Summary of Benefits will be sent to your child’s provider on the same day.

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Live Representative

Once you’re enrolled in the Ascendis Signature Access Program (A·S·A·P), you’ll receive one-on-one support when you need it.

Once your child is prescribed

Fill out the Patient Consent Form and email it to [email protected].
Or fax it to 1-888-436-0193. Questions? Please call 1-844-442-7236.

Download Patient Consent Form

Working with the
Ascendis Signature Access Program (A·S·A·P)

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Your A·S·A·P representative will be your single point of contact to help you with the following:

  • Exploring financial assistance
  • Scheduling a training on how to use the SKYTROFA Auto-Injector
  • Coordinating SKYTROFA Auto-Injector doorstep deliveries
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“Our experience with A·S·A·P has been phenomenal. It was very reassuring to know we weren’t alone in this process.”

–Nicole, Caregiver Ambassador

See Nicole’s Story
Individual results may vary

Paying for SKYTROFA

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You could pay as little as $5 per month

With the SKYTROFA Co-Pay Program, eligible patients may pay as little as $5 per month for a SKYTROFA prescription.† Contact A·S·A·P by calling 1-844-442-7236.

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SKYTROFA has broad insurance coverage

Watch this informative video to learn how to compare plans, participate in open enrollment, and get prior authorizations so your child can get started on the pediatric GHD treatment already prescribed to more than 10,000 children.*

Watch the 3 Cs of Health Insurance
* Numbers are based on Ascendis Signature Access Program (A·S·A·P) prescribing data as of September 24, 2025 † Click here for full terms and conditions and eligibility criteria.

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IMPORTANT SAFETY INFORMATION & USES

SKYTROFA is a prescription medicine used for:

  • the replacement of growth hormone in children 1 year old or older who weigh at least 26 pounds (11.5 kilograms) with growth hormone deficiency (GHD)
  • the replacement of growth hormone in adults with growth hormone deficiency (GHD)

Do not take SKYTROFA if:

  • you have a critical illness caused by certain types of heart or stomach surgery, trauma or breathing problems
  • you are allergic to somatropin or any of the ingredients in SKYTROFA
  • you are a child with closed bone growth plates
  • you have cancer or other tumors
  • you have certain types of eye problems caused by diabetes
  • you are a child with Prader-Willi syndrome who is severely obese or has breathing problems including sleep apnea (briefly stopping breathing during sleep)

Tell your healthcare provider if you are pregnant or plan to become pregnant, about all of your medical conditions, and about all the medicines you take. SKYTROFA may affect how other medicines work, and other medicines may affect how SKYTROFA works.

What are the possible side effects of SKYTROFA?

SKYTROFA may cause serious side effects, including:

  • serious allergic reactions. Get medical help right away if you have swelling of the face, mouth, tongue, or throat or trouble breathing
  • high risk of death in people who have critical illnesses caused by heart or stomach surgery, trauma, or serious breathing problems
  • increased risk of growth of an existing tumor or cancer, or increased risk of a previous tumor or cancer returning in people who were treated with radiation to the brain or head as children and who developed low growth hormone problems. Your healthcare provider will need to monitor for the growth or return of a tumor or cancer. Contact your healthcare provider if you start to have sudden changes in behavior, headaches, vision problems, or changes in moles, birthmarks, or skin color
  • new or worsening high blood sugar or diabetes. Your blood sugar may need to be monitored during treatment with SKYTROFA
  • increase in pressure in the skull. Contact your healthcare provider if headaches, eye problems, nausea, or vomiting occur
  • too much fluid in the body (fluid retention). Contact your healthcare provider if you notice swelling in the hands and feet, pain in the joints or muscles, or nerve problems that cause pain, burning or tingling in the hands, arms, legs, and feet
  • decrease in a hormone called cortisol. Your healthcare provider will do blood tests to check your cortisol levels
  • decrease in thyroid hormone levels. Decreased thyroid hormone levels may affect how well SKYTROFA works. Your healthcare provider will do blood tests to check your thyroid hormone levels
  • hip and knee pain or a limp in children (slipped capital femoral epiphysis). This may lead to a serious condition where bone tissue dies due to a lack of blood supply (osteonecrosis). Get medical help right away for children who develop a limp or have hip or knee pain
  • worsening of curvature of the spine in children (scoliosis)
  • severe and constant abdominal pain. This could be a sign of pancreatitis. Tell your healthcare provider about any new abdominal pain
  • loss of fat and tissue weakness in the area of skin you or your child inject. Talk to your healthcare provider about rotating the areas where SKYTROFA is injected
  • high risk of sudden death in children with Prader-Willi syndrome who are severely obese or have breathing problems, including sleep apnea
  • increase in phosphate, alkaline phosphatase, and parathyroid hormone levels in your blood. Your healthcare provider will do blood tests to check this

The most common side effects of SKYTROFA in children include: viral infection, fever, cough, nausea and vomiting, bleeding, diarrhea, stomach area pain, joint pain and arthritis

The most common side effects of SKYTROFA in adults include: swelling due to fluid build-up and low thyroid hormone

These are not all of the possible side effects of SKYTROFA. Call your doctor for medical advice about side effects. You are encouraged to report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. You may also report side effects to Ascendis Pharma at 1-844-442-7236.

Please click here for SKYTROFA full Prescribing Information.